8 Terms
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Cancer drugs
Drugs, agents used in the treatment of cancer or conditions related to cancer.
Industry: Pharmaceutical
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Cancer drugs
quinine
Pharmaceutical; Cancer drugs
A quinidine alkaloid isolated from the bark of the cinchona tree. Quinine has many mechanisms of action, including reduction of oxygen intake and carbohydrate metabolism; disruption of DNA ...
pan-HER/VEGFR2 receptor tyrosine kinase inhibitor BMS-690514
Pharmaceutical; Cancer drugs
A pyrrolotriazine-based compound and a pan inhibitor of receptor tyrosine kinases with potential antineoplastic activity. Pan HER/VEGFR2 receptor tyrosine kinase inhibitor BMS-690514 binds to human ...
pan HER/VEGFR2 receptor tyrosine kinase inhibitor BMS-690154
Pharmaceutical; Cancer drugs
A pyrrolotriazine-based compound and a pan inhibitor of receptor tyrosine kinases with potential antineoplastic activity. Pan HER/VEGFR2 receptor tyrosine kinase inhibitor BMS-690154 binds to human ...
SJG-136
Pharmaceutical; Cancer drugs
A pyrrolobenzodiazepine dimer with potential antineoplastic activity. SJG-136 binds to the minor groove of DNA and induces interstrand cross-links between two N-2 guanine positions, thereby ...
BIBX 1382
Pharmaceutical; Cancer drugs
A pyrimido-pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of the Epidermal Growth Factor Receptor (EGFR) thus specifically reversing the aberrant ...
thymidine
Pharmaceutical; Cancer drugs
A pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. As a constituent of DNA, thymidine pairs with adenine in the DNA double helix.
gimeracil
Pharmaceutical; Cancer drugs
A pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase ...
