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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

unresponsiveness

Biology; Immunology

Inability to respond to antigenic stimulus. Unresponsiveness may be specific for a particular antigen, or broadly nonspecific as a result of damage to the entire immune system, for example, after ...

V(D)J recombination

Biology; Immunology

Mechanism for generating antigen-specific receptors of T and B cells; it involves the joining of V, D, and J gene segments mediated by the enzyme complex V(D)J recombinase, and products of the RAG-1 ...

vaccination

Biology; Immunology

Any protective immunization against a pathogen. Originally referred to immunization against smallpox with the less virulent cowpox (vaccinia) virus.

variable (V) regions

Biology; Immunology

The N-terminal portion of an Ig or TCR which contains the antigen-binding region of the molecule; V regions are formed by the recombination of V(D) and J gene segments.

virion

Biology; Immunology

A complete virus particle.

virus

Biology; Immunology

An organism comprising a protein coat and DNA or RNA genome; it requires a host cell for replication.

Western blotting

Biology; Immunology

A technique to identify a specific protein in a mixture; proteins separated by gel electrophoresis are blotted onto a nitrocellulose membrane, and the protein of interest is detected by adding ...

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