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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
Add a new termContributors in Immunology
Immunology
T-cell receptor (TCR)
Biology; Immunology
A two-chain structure on T cells that binds antigen: αβ on the major set of T cells, γδ on the minor set of T cells. The TCR complex comprises the antigen-binding chains associated at the cell ...
T-dependent antigen
Biology; Immunology
An immunogen that requires T helper cells to interact with B cells in order to induce antibody synthesis.
terminal deoxynucleotidyl transferase (TDT)
Biology; Immunology
Enzyme that inserts nontemplated nucleotides at the junctions of V, D, and J gene segments of Ig and TCR locus DNA; these N-nucleotides increase the diversity of antigen-specific receptors.
thymus
Biology; Immunology
The primary lymphoid organ for T-cell differentiation, comprising an outer cortex and inner medulla; developing thymocytes interact with epithelial cells and bone marrow derived macrophages and ...
T-independent antigen
Biology; Immunology
An immunogen that induces antibody synthesis in the absence of T cells or their products; antibodies synthesized generally only of the IgM isotype, and no memory response.
titer
Biology; Immunology
Used generally as an empirical measure of the avidity of an antibody; it is the reciprocal of the last dilution of a titration giving a measurable effect; e.g., if the last dilution of an antibody ...
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