Molecular biology

Molecular biology

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Molecular biology

glucose effect

Biology; Biochemistry

The repression of some bacterial enzymes by the presence of glucose in the growth medium. Depression of cyclic AMP levels due to the availability of glucose is mediated by inhibition of adenylate ...

phase problem

Biology; Biochemistry

In X-ray crystallography, the gap between the requirements for reconstruction of a model - for each reflection (defined by the angle of its diffraction), the amplitude (related to intensity) and ...

A graphical method for determination of the type of enzyme inhibition and the dissociation constant for an enzyme-inhibitor complex (K i ) or for an enzyme-inhibitor-substrate complex (K i '). The ...

variable number tandem repeat (VNTR)

Biology; Biochemistry

A minisatellite DNA; the repetition of a 35-80bp sequence, to a size of up to 2kbp, that is characteristic of an individual. VNTRs are used in forensic science to identify, or exclude, suspects of a ...

molecular model

Biology; Biochemistry

A physical representation, e.g. balls and sticks, used to represent the structure of a compound or macromolecule, or a computer graphics simulation of such a structure. More sophisticated versions ...

Holliday model

Biology; Biochemistry

A conceptualization of general genetic recombination of newly replicated DNA during meiosis. An endonuclease nicks one strand of each of the two daughter duplexes at homologous sites which permits ...

Western blotting

Biology; Biochemistry

A technique to detect specific proteins. A mixture of proteins is separated by polyacrylamide-gel electrophoresis, blotted on to a plastic sheet (e.g. of nitrocellulose) and then exposed to a ...