COX-2 inhibitor

COX-2 inhibitor

A type of nonsteroidal anti-inflammatory drug (NSAID) designed to be safer for the stomach than other NSAIDs. COX-2 inhibitors work by inhibiting hormonelike substances in the body that cause pain and inflammation without interfering with similar substances that protect the stomach lining. Celecoxib (Celebrex) is the only COX-2 inhibitor currently available. Two others, rofecoxib (Vioxx) and valdecoxib (Bextra), were withdrawn from the market when it was discovered they increased risks from heart disease.

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Category: Arthritis
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