Molecular biology

Molecular biology

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Molecular biology

creatine kinase

Biology; Biochemistry

An enzyme that catalyzes the reversible reaction of creatine plus ATP to phosphocreatine (PCr) and ADP. Creatine kinase concentrations are elevated after myocardial infarction or other conditions ...

The reversible condensation of the carbonyl group of a sugar with an amino group of a protein to form a Schiff base that often triggers subsequent irreversible rearrangements, e.g. the condensation ...

freeze-fracture

Biology; Biochemistry

A technique to prepare cells for scanning electron microscopy; cleavage of a solidly frozen cell, followed by freeze-etching, i.e. sublimation of some of the frozen water of the cell and coating the ...

ab initio

Biology; Biochemistry

From the beginning, as opposed to pre-existing, e.g. and ab initio complex is one that is assembled from its completely separated subunits, or an ab initio calculation is one that is constructed from ...

receptor

Biology; Biochemistry

The binding site for a hormone or neurotransmitter that initiates its action at the cellular level. First proposed about a century ago to fulfill the postulate that agents may act only if they can ...

amplification

Biology; Biochemistry

The causation of a quantitatively major biochemical or physiological event by a quantitatively minor initiator, e.g. the blood clotting cascade, ion gating; also, using the polymerase chain reaction, ...

bioavailability

Biology; Biochemistry

The ease of access a drug or nutrient may have to its site of biological action; e.g. the ability of an antisense oligonucleotide designed to target a neuroreceptor to cross the blood-brain barrier, ...