Home > Blossary: Antihypertensive drugs
More than one in three adults worldwide have raised blood pressure – a condition that causes around half of all deaths from stroke and heart disease. It is considered directly responsible for 7.5 million deaths in 2004 – almost 13% of all global deaths. In nearly all high-income countries, widespread diagnosis and treatment with low-cost medication have led to a dramatic drop in mean blood pressure across populations – and this has contributed to a reduction in deaths from heart disease.

Category: Health

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Created by: marija.horvat

Number of Blossarys: 21

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Hypertension, also referred to as high blood pressure, is a condition in which the arteries have persistently elevated blood pressure. Every time the human heart beats, it pumps blood to the whole ...

Domain: Health care; Category: Pharmacy

Endothelin receptor antagonists, by blocking the vasoconstrictor and cardiotonic effects of ET-1, produce vasodilation and cardiac inhibition. Endothelin receptor antagonists have been shown to ...

Domain: Health care; Category: Pharmacy

Alpha-adrenoceptor agonists (α-agonists) bind to α-receptors on vascular smooth muscle and induce smooth contraction and vasoconstriction, thus mimicking the effects of sympathetic adrenergic nerve ...

Domain: Health care; Category: Pharmacy

Aldosterone receptor antagonists are medicines that help the body get rid of extra water (diuretics). They also have other properties that can prevent heart failure from becoming worse, along with ...

Domain: Health care; Category: Pharmacy

Renin inhibitors produce vasodilation by inhibiting the activity of renin, which is responsible for stimulating angiotensin II formation. Renin is a proteolytic enzyme that is released by the kidneys ...

Domain: Health care; Category: Pharmacy

Although controversial over this off-label purpose, benzodiazepines may play a role in lowering blood pressure. They work as an agonist of the GABA-a receptors in the brain, thus slowing down ...

Domain: Health care; Category: Pharmacy

Vasodilatators act directly on the smooth muscle of arteries to relax their walls so blood can move more easily through them; they are only used in hypertensive emergencies or when other drugs have ...

Domain: Health care; Category: Pharmacy

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