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Biology

A natural science concerned with the study of life or living matter in all its forms and phenomena, especially in relation to their origin, growth, reproduction, structure, behaviour and evolution.

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Biology > Immunology

unresponsiveness

Biology; Immunology

Inability to respond to antigenic stimulus. Unresponsiveness may be specific for a particular antigen, or broadly nonspecific as a result of damage to the entire immune system, ...

V(D)J recombination

Biology; Immunology

Mechanism for generating antigen-specific receptors of T and B cells; it involves the joining of V, D, and J gene segments mediated by the enzyme complex V(D)J recombinase, and ...

vaccination

Biology; Immunology

Any protective immunization against a pathogen. Originally referred to immunization against smallpox with the less virulent cowpox (vaccinia) virus.

variable (V) regions

Biology; Immunology

The N-terminal portion of an Ig or TCR which contains the antigen-binding region of the molecule; V regions are formed by the recombination of V(D) and J gene segments.

virion

Biology; Immunology

A complete virus particle.

virus

Biology; Immunology

An organism comprising a protein coat and DNA or RNA genome; it requires a host cell for replication.

Western blotting

Biology; Immunology

A technique to identify a specific protein in a mixture; proteins separated by gel electrophoresis are blotted onto a nitrocellulose membrane, and the protein of interest is ...