Biology

Biology

A natural science concerned with the study of life or living matter in all its forms and phenomena, especially in relation to their origin, growth, reproduction, structure, behaviour and evolution.

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Biology > Immunology

isotype switch

Biology; Immunology

The switch which occurs when a B cell stops secreting antibody of one isotype or class and starts producing antibody of a different isotype but with same antigenic specificity; ...

isotypes

Biology; Immunology

Also known as antibody classes. Antibodies that differ in the heavy chain constant regions: IgM, IgG, IgD, IgA and IgE. These differences result in distinct biological activities ...

J chain (joining chain)

Biology; Immunology

A polypeptide involved in the polymerization of IgM and IgA.

J gene

Biology; Immunology

A gene segment coding for the J or joining segment in immunoglobulin or T-cell receptor chains; in Ig light chains and TCR α and γ, a V gene segment rearranges to a J segment; in ...

Janus kinases (JAK)

Biology; Immunology

Tyrosine kinases activated by cytokines binding to their cellular receptors.

killer inhibitory receptor (KIR)

Biology; Immunology

a receptor expressed on NK cells that binds to MHC class I molecules on target cells; ligation of MHC class I inhibits the signaling that would otherwise lead to target cell ...