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Biology

A natural science concerned with the study of life or living matter in all its forms and phenomena, especially in relation to their origin, growth, reproduction, structure, behaviour and evolution.

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Biology > Immunology

C5 convertase

Biology; Immunology

A molecular complex that splits C5 into C5a and C5b in both the classical and the alternative pathway of complement activation.

C5 deficiency

Biology; Immunology

A very uncommon genetic disorder that has an autosomal recessive mode of inheritance. Individuals with this deficiency have a defective ability to form the membrance attack ...

complement component 5b (C5b)

Biology; Immunology

The principal molecular product that remains after C5a has been split off by the action of C5 convertase on C5. It has a binding site for complement component C6 and complexes ...

complement component 6 (C6)

Biology; Immunology

A complement component that participates in the membrane attack complex (MAC).

C6 deficiency

Biology; Immunology

A very uncommon genetic defect that has an autosomal recessive mode of inheritance in which affected individuals have only trace amounts of C6 in their plasma. They are defective ...

complement component 7 (C7)

Biology; Immunology

A complement component that forms a complex with C5b67 is formed when C7 binds to C5b and C6. The complex has the appearance of a stalk with a leaf type of structure.

C7 deficiency

Biology; Immunology

A very uncommon genetic disorder with an autosomal recessive mode of inheritance in which the serum of affected persons contains only trace amounts of C7 in the plasma. They have ...