Biochemistry

Biochemistry

The scientific study of the chemistry of living matter.

Industry: Biology; Biotechnology

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Biochemistry

furanose

Biology; Biochemistry

The form of a sugar when it is condensed into a 5-membered ring. By analogy with furane, the 5-membered cyclic compound containing an oxygen atom and two conjugated carbon-carbon double bonds, a ...

One of the two classes of heterocyclic organic bases that are found in nucleic acids (principally adenine and guanine) and in several other kinds of biological compounds, e.g. coenzymes, nucleotides, ...

transamination

Biology; Biochemistry

The concurrent amination and reduction of a carbonyl of one compound as another is deaminated and oxidized; especially the conversion of one α-amino acid into its corresponding α-oxo acid as another ...

representation

Biology; Biochemistry

A portion of the genome with lowered complexity (e.g. by cleavage with an infrequent cutting restriction nuclease, ligated to oligonucleotide adapters so it can then be amplified by PCR), but that ...

molecular ruler

Biology; Biochemistry

A method for measurement of distances on a molecular scale; the estimation of distances between a fluorescence energy donor and receptor, evaluated from the efficiency of resonance energy transfer, ...

single-strand conformational polymorphism (SSCP)

Biology; Biochemistry

A technique for detection of mutations in a defined DNA sequence. A labelled PCR-amplified segment of DNA is heat-denatured then quenched at 08C, and the resultant single-stranded polynucleotides are ...

mismatched PCR

Biology; Biochemistry

A method for detection of a point mutation that neither produces nor destroys a restriction site; intended especially for screening large numbers of individuals. One of the PCR primers is designed so ...