Biochemistry

Biochemistry

The scientific study of the chemistry of living matter.

Industry: Biology; Biotechnology

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Biochemistry

amphitropic

Biology; Biochemistry

Having an affinity for both lipid and aqueous environments, e.g. a membrane-associated protein that has domains that are embedded in the membrane and others that extend into the cytoplasm or the ...

The amide bond formed by condensation of the α-carboxy group of one amino acid with the α-amino group of another; the bond that joins together the amino acid residues that comprise a protein, peptide ...

gene amplification

Biology; Biochemistry

The synthesis of multiple copies of a specific gene, which remain as tandem repeats within the chromosome or are segregated as satellite DNA. Amplification is usually not inherited, in contrast to ...

homologous replacement

Biology; Biochemistry

A method to alter a cell's genome by introduction of a vector into the nucleus of a targeted germ or somatic cell, where it can pair with the cognate sequence of the chromosomal DNA and replace the ...

glycoprotein hormone

Biology; Biochemistry

A representative of a class of hormones that share nearly identical A-chains and unique B-chains, each with about 125 amino acid residues and N-linked or O-linked carbohydrate moieties, e.g. ...

HTF island

Biology; Biochemistry

A tiny fragment, 1000-2000bp long, generated by action of the restriction nuclease HpaII; usually found associated with expressed genes; characterized by the relatively rare CpG dinucleotide that ...

acyl-enzyme

Biology; Biochemistry

An intermediate in the hydrolysis of substrates by some peptidases and esterases, e.g. by serine proteinases, in which the acyl moiety of the substrate is transiently attached to a serine hydroxy ...