Biochemistry

Biochemistry

The scientific study of the chemistry of living matter.

Industry: Biology; Biotechnology

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Biochemistry

digestibility

Biology; Biochemistry

The characteristic of a protein that accounts for its nutritional quality according to how efficiently its digestion delivers its amino acids, especially the essential amino acids, to the individual.

licencing

Biology; Biochemistry

The limiting of replication of the eukaryotic genome to once per cell cycle. The proteins that impose this effect are termed replication licencing factors (RLFs), but their mode of action is unknown.

pKa

Biology; Biochemistry

The negative of the common logarithm of the dissociation constant of an acid; i.e. -logK a , where K a =(H + )(A - )/(HA) for (HA)=(H + )+(A - ).

donor (5') splice site

Biology; Biochemistry

The site on pre-mRNA that corresponds to the 3'-end of an exon and the 5'-end of an intron. The first two bases of the intron at the donor splice site are GU in most cases, but AU in some instances.

beta (β)-barrel

Biology; Biochemistry

A form of supersecondary structure: a structure within a globular protein in which six or more extended polypeptide strands (β-pleated sheets) are arrayed cylindrically to form the staves of a ...

Ramachandran plot

Biology; Biochemistry

A graph that displays calculated energy isotherms for conformations of peptide backbones; phi-angles against psi-angles; energy minima correspond to β-structure, α-helix and the collagen triple ...

double duplex invasion

Biology; Biochemistry

A mechanism by which a pair of pseudocomplementary protein nucleic acids (PNAs) target and inactivate DNA. The DNA strands are unwound locallly and each is targeted simultaneously by one of the PNAs.