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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

humanization

Biology; Immunology

Refers to the genetic engineering by which mouse V(D)J region genes defining a particular antigenic specificity are combined with human genes coding for the rest of the Ig molecule. Results in an ...

humoral immunity

Biology; Immunology

refers to immune responses that involve antibody (contrast with cell-mediated immunity: T-cell responses in the absence of antibody). Can be transferred to another individual using antibody-containing ...

dendritic cells

Biology; Immunology

Interdigitating reticular cells, derived from bone-marrow precursors, that are found in T-cell areas of lymphoid tissues. They have a branched or dendritic morphology and are the most potent ...

desensitization

Biology; Immunology

A procedure in which allergic individuals are exposed to increasing doses of allergen with the goal of inhibiting their allergic reactions. The mechanism responsible for this effect probably involves ...

determinant

Biology; Immunology

Part of the antigen molecule that binds to an antibody-combining site or to a receptor on T cells; also termed epitope.

diapedesis

Biology; Immunology

is the movement of blood cells, particularly leukocytes, from the blood across blood vessel walls into tissues.

differentiation antigen

Biology; Immunology

A cell-surface antigenic determinant found only on cells of a certain lineage and at a particular developmental stage; used as an immunologic marker.

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