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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

immunoglobulin superfamily

Biology; Immunology

Proteins involved in cellular recognition and interaction that are structurally and genetically related to immunoglobulins.

immunoreceptor tyrosine-based activation motif (ITAM)

Biology; Immunology

A pattern of amino acids in the cytoplasmic tail of many transmembrane receptor molecules, including Igα and Igβ and CD3 chains, which are phosphorylated and then associate with intracellular ...

immunoreceptor tyrosine-based inhibitory motif (ITIM)

Biology; Immunology

A pattern of amino acids in the cytoplasmic tail of transmembrane molecules, such as CD32, which negatively regulates cell activation. The ITIM bonds a phosphatase which removes phosphate groups from ...

inflammation

Biology; Immunology

An acute or chronic response to tissue injury or infection involving accumulation of leukocytes, plasma proteins, and fluid.

innate immunity

Biology; Immunology

The antigen-nonspecific mechanisms involved in the early phase of resistance to a pathogen, which include phagocytic cells, cytokines, and complement; not expanded by repeat stimulation with the ...

integrins

Biology; Immunology

A family of two-chain cell-surface adhesion molecules found on leukocytes; important in the adhesion of APC and lymphocytes, and in leukocyte migration into tissues.

intercellular adhesion molecules (ICAMs) 1, 2, and 3

Biology; Immunology

Adhesion molecules on the surface of several cell types, including antigen-presenting cells and T cells that interact with integrins; members of the immunoglobulin superfamily. (fp

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