Leukemia

Leukemia

The prevention and treatment of leukemia -- cancer of the blood or bone marrow. The disease is characterized by an abnormal increase of immature white blood cells.

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Leukemia

Abl

Health care; Leukemia

The designation of the human proto-oncogene located on chromosome 9 that is mutated by the translocation of a piece of chromosome 9 to chromosome 22 in CML and some cases of acute lymphoblastic ...

thrombosis

Health care; Leukemia

The development of a clot in a vein or an artery.

blast cells

Health care; Leukemia

The earliest marrow cells identified by the light microscope. Blasts represent about 1 percent of normally developing marrow cells. They are largely myeloblasts, which are cells that will develop ...

iliac crest

Health care; Leukemia

The edge of the hip bone from which marrow is usually sampled for diagnosis of blood cell diseases.

lymph node drainage

Health care; Leukemia

The flow of lymph from an area of tissue into a particular lymph node.

retinoic acid receptor alpha gene (RAR-α)

Health care; Leukemia

The gene for the retinoic acid receptor that is disrupted in the translocation between chromosome 15 and 17 in acute promyelocytic leukemia.

breakpoint cluster region protein (BCR)

Health care; Leukemia

The gene on chromosome 22 that is disrupted by the formation of the Philadelphia chromosome. The translocated ABL gene from chromosome 9 fuses with the remaining portion of the reciprocally ...