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Leukemia
The prevention and treatment of leukemia -- cancer of the blood or bone marrow. The disease is characterized by an abnormal increase of immature white blood cells.
Industry: Health care
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Leukemia
Abl
Health care; Leukemia
The designation of the human proto-oncogene located on chromosome 9 that is mutated by the translocation of a piece of chromosome 9 to chromosome 22 in CML and some cases of acute lymphoblastic ...
blast cells
Health care; Leukemia
The earliest marrow cells identified by the light microscope. Blasts represent about 1 percent of normally developing marrow cells. They are largely myeloblasts, which are cells that will develop ...
iliac crest
Health care; Leukemia
The edge of the hip bone from which marrow is usually sampled for diagnosis of blood cell diseases.
lymph node drainage
Health care; Leukemia
The flow of lymph from an area of tissue into a particular lymph node.
retinoic acid receptor alpha gene (RAR-α)
Health care; Leukemia
The gene for the retinoic acid receptor that is disrupted in the translocation between chromosome 15 and 17 in acute promyelocytic leukemia.
breakpoint cluster region protein (BCR)
Health care; Leukemia
The gene on chromosome 22 that is disrupted by the formation of the Philadelphia chromosome. The translocated ABL gene from chromosome 9 fuses with the remaining portion of the reciprocally ...
