Home > Terms > English (EN) > immunoglobulin E (IgE)

immunoglobulin E (IgE)

IgE a type of antibody produced by IgE plasma cells. These are specialized B-cell lymphocytes that make free-floating antibodies for what is termed humoral resistance. IgE is peculiar for several reasons. It is not made to be specific against only one antigen like other gamma globulins, but instead can bind with a number of dangerous proteins. Further, IgE travels to mast cells, sticks to their surfaces, and when antigens get stuck to the IgE, the mast cells secrete inflammatory compounds like histamine. Since IgE is a generalist, coded for a number of potential toxins, not just a single substance, it can decide that Juniper pollen and cat dander are antigens...and you have an allergy. Elevated production of IgE is often inherited, which is why allergies run in a family-and why, once you have an allergy, the mast cells and IgE can decide that, for the duration, a whole bunch of other stuff causes hypersensitivity reactions, stuff that wouldn't normally bother you without an ongoing allergy.

  • Part of Speech: noun
  • Synonym(s):
  • Blossary:
  • Industry/Domain: Medical
  • Category: Herbal medicine
  • Company:
  • Product:
  • Acronym-Abbreviation:
Collect to Blossary

Member comments

You have to log in to post to discussions.

Terms in the News

Billy Morgan

Sports; Snowboarding

British snowboarder Billy Morgan has landed the sport’s first ever 1800 quadruple cork. The rider, who represented Great Britain at the 2014 Winter Olympics in Sochi, was in Livigno, Italy, when he achieved the manoeuvre. It involves flipping four times, while the body also spins five complete rotations on a sideways or downward-facing axis. The trick had ...

Marzieh Afkham

Broadcasting & receiving; News

Marzieh Afkham, who is the country’s first foreign ministry spokeswoman, will head a mission in east Asia, the state news agency reported. It is not clear to which country she will be posted as her appointment has yet to be announced officially. Afkham will only be the second female ambassador Iran has had. Under the last shah’s rule, Mehrangiz Dolatshahi, a ...

Weekly Packet

Language; Online services; Slang; Internet

Weekly Packet or "Paquete Semanal" as it is known in Cuba is a term used by Cubans to describe the information that is gathered from the internet outside of Cuba and saved onto hard drives to be transported into Cuba itself. Weekly Packets are then sold to Cuban's without internet access, allowing them to obtain information just days - and sometimes hours - after it ...

Asian Infrastructure Investment Bank (AIIB)

Banking; Investment banking

The Asian Infrastructure Investment Bank (AIIB) is an international financial institution established to address the need in Asia for infrastructure development. According to the Asian Development Bank, Asia needs $800 billion each year for roads, ports, power plants or other infrastructure projects before 2020. Originally proposed by China in 2013, a signing ...


Online services; Internet

Spartan is the codename given to the new Microsoft Windows 10 browser that will replace Microsoft Windows Internet Explorer. The new browser will be built from the ground up and disregard any code from the IE platform. It has a new rendering engine that is built to be compatible with how the web is written today. The name Spartan is named after the ...

Featured Terms

  • 274


  • 40


  • 8


Industry/Domain: Manufacturing Category: Glass

Gorilla Glass 3 with NDR

Corning is continually looking for ways to improve Gorilla Glass and achieve new levels of tough. Gorilla® Glass 3 is not only chemically strengthened ...

Contributors in Medical

Featured blossaries

Rediculous Celebrity Kids Names

Category: Arts   2 3 Terms

Animals' Etymology

Category: Animals   1 13 Terms