cot curve

cot curve

When duplex DNA is heated, it dissociates into single strands. When the temperature is lowered, complementary strands tend to anneal or re-nature. The extent of re-naturation depends on the product of DNA concentration in moles of nucleotides per litre, and time in seconds. A graph showing the proportion of re-natured DNA against cot is known as a cot curve. The cot at which half the DNA has re-natured is the half-cot, a parameter indicating the degree of complexity of the DNA.

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Industry/Domain: Biotechnology
Category: Genetic engineering
Organization: FAO
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Related terms

cot

Personal life; Funeral

The stretcher-like carrier used to remove deceased persons from the place of death to the funeral home.

cot

Textiles; Manufactured fibers

The covering material used on various fiber-processing rolls, especially drawing rolls. Leather, cork, rubber, and synthetic materials are frequently employed.

cot

Language; Dictionaries

A sleeping place of limited size; a little bed; a cradle; a piece of canvas extended by a frame, used as a bed.

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