Biology

Biology

A natural science concerned with the study of life or living matter in all its forms and phenomena, especially in relation to their origin, growth, reproduction, structure, behaviour and evolution.

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Biology > Immunology

calnexin

Biology; Immunology

The protein calnexin is an 88 kDa protein found in the endoplasmic reticulum. It binds to partly folded members of the immunoglobulin superfamily of proteins and retains them in ...

MHC haplotype

Biology; Immunology

MHC genes are inherited in most cases as an MHC haplotype, the set of genes in a haploid genome inherited from one parent. Thus, if the parents are designated as ab and cd, then ...

MHC:peptide tetramers

Biology; Immunology

The development of MHC:peptide tetramers held together by fluorescent streptavidin, which has four binding sites for the biotin attached to the tail of the MHC molecule, has made ...

B-cell lymphoma 2 (Bcl-2)

Biology; Immunology

The protein known as Bcl-2 protects cells from apoptosis by binding to the mitochondrial membrane. It is encoded by the bcl-2 gene, which was discovered at the breakpoint of an ...

L-selectin

Biology; Immunology

L-selectin is an adhesion molecule of the selectin family found on lymphocytes. L-selectin binds to CD34 and GlyCAM-1 on high endothelial venules to initiate the migration of ...

common γ chain

Biology; Immunology

The common γ chain (γc) is a transmembrane polypeptide chain (CD132) that is common to a subgroup of class I cytokine receptors. It plays a key role in the intracellular signaling ...

agonist peptides

Biology; Immunology

Agonist peptides are peptide antigens that activate their specific T cells, inducing them to make cytokines and to proliferate. They are thought to differ from antagonist peptides ...