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Biology
A natural science concerned with the study of life or living matter in all its forms and phenomena, especially in relation to their origin, growth, reproduction, structure, behaviour and evolution.
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high endothelial venules
Biology; Immunology
High endothelial venules (HEVs) are specialized venules found in lymphoid tissues. Lymphocytes migrate from blood into lymphoid tissues by attaching to and migrating across the ...
western blotting
Biology; Immunology
In Western blotting, a mixture of proteins is separated, usually by gel electrophoresis and transferred by blotting to a nitrocellulose membrane; labeled antibodies are then used ...
intracellular cytokine staining
Biology; Immunology
Staining for cytokines in cells that produce them can be achieved by permiablizing the cell and reacting it with a labelled fluorescent anti-cytokine antibody. This procedure is ...
insulin-dependent diabetes mellitus
Biology; Immunology
In insulin-dependent diabetes mellitus (IDDM), the β cells of the pancreatic islets of Langerhans are destroyed so that no insulin is produced. The disease is believed to result ...
C domains
Biology; Immunology
The constant regions of the polypeptide chains of immunoglobulin molecules are made up of one or more constant domains or C domains of similar structure; each immunoglobulin chain ...
V domain
Biology; Immunology
The variable region of the polypeptide chains of an immunoglobulin or T-cell receptor is composed of a single N-terminal V domain. Paired V domains form the antigen-binding sites ...
pro-B cells
Biology; Immunology
During B-cell development, pro-B cells are cells that have displayed B-cell surface marker proteins but have not yet completed heavy-chain gene rearrangement. They are divided ...
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