Biology

Biology

A natural science concerned with the study of life or living matter in all its forms and phenomena, especially in relation to their origin, growth, reproduction, structure, behaviour and evolution.

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Biology > Immunology

prednisone

Biology; Immunology

Prednisone is a synthetic steroid with potent anti-inflammatory and immunosuppressive activity used in treating acute graft rejection, autoimmune disease, and lymphoid tumors.

stromal cells

Biology; Immunology

The development of B lymphocytes and T lymphocytes occurs in association with stromal cells, which provide various soluble and cell-bound signals to the developing lymphocyte.

signal joint

Biology; Immunology

A signal joint is formed by the precise joining of recognition signal sequences in the process of somatic recombination that generates T-cell receptor and immunoglobulin genes.

antagonist peptides

Biology; Immunology

Antagonist peptides are peptides, usually closely related in sequence to an agonist peptide, that inhibit the response of a cloned T-cell line specific for the agonist peptide.

inducible costimulator (ICOS)

Biology; Immunology

ICOS is a CD28-related protein that is induced on activated T cells and can enhance T-cell responses. It binds a ligand known as LICOS, which is distinct from the B7 molecules.

polygenic

Biology; Immunology

The major histocompatibility complex is both polygenic, containing several loci encoding proteins of identical function, and polymorphic, having multiple alleles at each locus.

nude

Biology; Immunology

The nude mutation of mice produces hairlessness and defective formation of the thymic stroma, so that nude mice, which are homozygous for this mutation, have no mature T cells.