Genetics

Genetics

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Genetics

Microarray (DNA)

Biology; Genetics

Miniaturized array of a large number (usually thousands) of unique DNA sequences, commonly representing specific genes, attached to a solid substrate. Often used to simultaneously monitor the ...

Region of non-coding DNA consisting of specific short sequences (usually 1-5 base-pairs) repeated sequentially many times. The number of repeats in each microsatellite varies widely among different ...

Multipotent

Biology; Genetics

Class of stem cells that can differentiate into more than one tissue type of closely related cells, but not all. Descendents of pluripotent stem cells.

Mutation

Biology; Genetics

Any heritable change in the DNA sequence; usually refers to a rare and harmful change in the DNA sequence that is present in less than 1% of the population.

Negative predictive value (NPV)

Biology; Genetics

Probability of an individual not having a particular disorder following a negative test, i.e. the proportion of true negative results relative to the total number of negative tests. As the prevalence ...

Non-coding

Biology; Genetics

Region of the DNA sequence which does not contain any genes, i.e. does not code for the production of a protein. Around 99% of the human genetic code is thought to be non-coding.

Nucleotide

Biology; Genetics

The molecular unit from which DNA and RNA are made. In DNA, a nucleotide consists of a 'base' [adenine (A), guanine (G), cytosine (C) or thymine (T)] linked to the sugar deoxyribose and a phosphate ...