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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

serum sickness

Biology; Immunology

A type III hypersensitivity reaction resulting from deposition of circulating, soluble, antigen-antibody complexes leading to complement and neutrophil activation in tissues such as the kidney; ...

severe combined immune deficiency (SCID)

Biology; Immunology

Disease resulting from early block in differentiation pathways of both B and T lymphocytes.

signal transducers and activators of transcription (STATs)

Biology; Immunology

Intracellular proteins phosphorylated by Janus kinases as a consequence of cytokine-cytokine receptor engagement.

signal transduction

Biology; Immunology

Processes involved in transmitting the signal received on the outer surface of the cell (e.g., by antigen binding to its receptor) into the nucleus of the cell, which lead to altered gene expression.

slow-reacting substance of anaphylaxis (SRS-A)

Biology; Immunology

A group of leukotrienes released by mast cells during anaphylaxis that induces a prolonged contraction of smooth muscle.

somatic gene conversion

Biology; Immunology

nonreciprocal exchange of sequences between genes: part of the donor gene or genes is "copied" into an acceptor gene, but only the acceptor gene is altered; mechanism for generating diverse Ig ...

somatic hypermutation

Biology; Immunology

Change in the variable region sequence of an antibody produced by a B cell following antigenic stimulation, resulting in increased antibody affinity for antigen.

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