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Molecular biology
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Molecular biology
Xenopus oocyte
Biology; Biochemistry
An egg of the African clawed frog, Xenopus laevis; a favored heterologous expression system that, because of its large size, can be microinjected with cDNA or mRNA and monitored for synthesis of a ...
amphitropic
Biology; Biochemistry
Having an affinity for both lipid and aqueous environments, e.g. a membrane-associated protein that has domains that are embedded in the membrane and others that extend into the cytoplasm or the ...
peptide bond
Biology; Biochemistry
The amide bond formed by condensation of the α-carboxy group of one amino acid with the α-amino group of another; the bond that joins together the amino acid residues that comprise a protein, peptide ...
gene amplification
Biology; Biochemistry
The synthesis of multiple copies of a specific gene, which remain as tandem repeats within the chromosome or are segregated as satellite DNA. Amplification is usually not inherited, in contrast to ...
homologous replacement
Biology; Biochemistry
A method to alter a cell's genome by introduction of a vector into the nucleus of a targeted germ or somatic cell, where it can pair with the cognate sequence of the chromosomal DNA and replace the ...
glycoprotein hormone
Biology; Biochemistry
A representative of a class of hormones that share nearly identical A-chains and unique B-chains, each with about 125 amino acid residues and N-linked or O-linked carbohydrate moieties, e.g. ...
HTF island
Biology; Biochemistry
A tiny fragment, 1000-2000bp long, generated by action of the restriction nuclease HpaII; usually found associated with expressed genes; characterized by the relatively rare CpG dinucleotide that ...
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