Molecular biology

Molecular biology

Industry: Biology

Add a new term

Contributors in Molecular biology

Become a Contributors

Molecular biology

kinetic proofreading

Biology; Biochemistry

A mechanism for assuring fidelity in directed macromolecular synthesis; e.g. in protein synthesis a well matched anti-codon-codon pair, as opposed to a poorly matched pair, will remain associated ...

Allosteric regulation; the modification of binding or catalytic properties of a protein by binding of a regulator at a site distinct from the ligand- or substrate-binding site. Allostery typically ...

allosteric effector

Biology; Biochemistry

A compound that modifies the activity of an enzyme, or its affinity for its substrate, by binding to a site distinct from the active site; a positive effector increases the activity, a negative ...

allosteric regulation

Biology; Biochemistry

The modification of binding or catalytic properties of a protein by attachment of a regulator at a site distinct from the ligand- or substrate-binding site. Allostery typically results in sigmoidal ...

high-energy bond

Biology; Biochemistry

A chemical bond whose hydrolysis results in the generation of ≧30kJ (7kcal) of energy or, if coupled to an energetically unfavorable reaction, can drive that reaction forward. Examples are found in ...

optimal matching hydrophobicity (OMH)

Biology; Biochemistry

A calculated value used to predict conformational similarities of proteins from their amino acid sequences. Numerical values for hydrophobicity, OMHs, are assigned to each amino acid residue to allow ...

area detector

Biology; Biochemistry

An 'electronic film'; a device for measurement of diffracted radiation, e.g. in X-ray crystallographic analysis; detector devices are densely arrayed over a screen and report to a computer the ...