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leprosy

Leprosy is caused by Mycobacterium leprae and occurs in a variety of forms. There are two polar forms: lepromatous leprosy, which is characterized by abundant replication of leprosy bacilli and abundant antibody production without cell-mediated immunity; and tuberculoid leprosy, in which few organisms are seen in the tissues, there is little or no antibody, but cell-mediated immunity is very active. The other forms of leprosy are intermediate between the polar forms.

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