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walang kabuluhang pagbago
Isang hene na pagbago kung saan ang isang batayang pares na pagbabago sa DNA ang dahilan ng pagbabago sa mRNA isang kodon mula sa isang amino asidong kodigo na kodon ng kuwintas-pagwawakas (katarantaduhan) codon. Bilang isang resulta, ang polipetid na kadinang pagbubuo ay tinapos ng mas maaga at samakatuwid alinman sa hindi gumagana o, sa pinakamahusay, bahagyang gumagana.
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