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connective tissue

Medical; Human genome

1) Tissue that supports and binds other tissues. It consists of connective tissue cells embedded in a large amount of extracellular matrix. 2) Supporting tissue that surrounds ...

comparative genomic hybridization

Medical; Human genome

1) Comparative genomic hybridization (CGH) is a technique that allows the detection of losses and gains in DNA copy number across the entire genome without prior knowledge of ...

cones

Medical; Human genome

1) One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less ...

chromatin remodeling

Medical; Human genome

1) Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional ...

dominant negative mutation

Medical; Human genome

A mutation whose gene product adversely affects the normal, wild-type gene product within the same cell, usually by dimerizing (combining) with it. In cases of polymeric ...

erythroblast

Medical; Human genome

A polychromatic nucleated cell of red marrow that synthesizes hemoglobin and that is an intermediate in the initial stage of red blood cell formation; broadly: a cell ancestral to ...

flanking microsatellite analysis

Medical; Human genome

The use of highly variable repetitive sequences found in microsatellite regions adjacent to genes or other areas of interest as markers for linkage analysis, DNA fingerprinting, ...