Biochemistry

Biochemistry

The scientific study of the chemistry of living matter.

Industry: Biology; Biotechnology

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Biochemistry

heterogeneous

Biology; Biochemistry

Descriptive of a diversity according to some criterion for detecting it; e.g. a mixture of proteins or polynucleotides of differing electrophoretic mobility, size or sequence. Heterogeneity is ...

The site of interaction between two double-stranded DNA molecules; at regions where the two double strands are homologous, equivalent strands of each duplex break and exchange complementary strands ...

immobile DNA junction

Biology; Biochemistry

A branched double-stranded DNA structure, a chi-form in which each of four polynucleotide chains is complementary to and base-paired with the 3'-end of one polynucleotide and the 5'-end of another; ...

illegitimate recombination

Biology; Biochemistry

Recombination with non-homologous regions of DNA. Each of the polynucleotide strands of double-stranded DNA is religated with DNA from different regions of the same or different chromosomes.

positive and negative selection (PNS)

Biology; Biochemistry

A technique to target insertion of a gene at a specific locus in a cell's genome. A plasmid is constructed in which a gene that allows positive selection (e.g. neomycin resistance) is inserted within ...

ribonucleic acid (RNA)

Biology; Biochemistry

A macromolecule formed of repeating riboses linked by phosphodiester bonds between the 3-hydroxyl group of one and the 5-hydroxyl group of the next. A purine, adenine or guanine, or a pyrimidine, ...

circular dichroism (CD)

Biology; Biochemistry

A technique for determination of the asymmetry of a molecule. Unlike in a conventional polarimeter, where light is restricted to oscillation in a plane, in CD the direction of oscillation turns ...