Cancer drugs

Cancer drugs

Drugs, agents used in the treatment of cancer or conditions related to cancer.

Contributors in Cancer drugs

Cancer drugs

A second generation, replication-competent adenovirus type 5 containing a yeast cytosine deaminase(yCD)/mutant sr39 herpes simplex virus thymidine kinase fusion (yCD/mutTKsr39) gene and the 11. 6 kDa ...

PI3Ka/mTOR inhibitor PKI-179

Pharmaceutical; Cancer drugs

A second generation, small-molecule mimetic of ATP that targets the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. PKI-179 selectively inhibits mTOR and ...

Smac mimetic GDC-0152

Pharmaceutical; Cancer drugs

A second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity. Smac mimetic GDC-0152 binds to the Smac binding ...

gataparsen sodium

Pharmaceutical; Cancer drugs

A second-generation antisense oligonucleotide directed against survivin mRNA with potential antitumor activity. Gataparsen sodium hybridizes to survivin mRNA, thereby blocking translation of survivin ...

Hsp27 antisense oligonucleotide OGX-427

Pharmaceutical; Cancer drugs

A second-generation antisense oligonucleotide targeting heat shock protein 27 (Hsp27) with potential antitumor and chemosensitizing activities. Hsp27 antisense oligonucleotide OGX-427 suppresses ...

antisense oligonucleotide ISIS EIF4ERx

Pharmaceutical; Cancer drugs

A second-generation antisense oligonucleotide targeting the eukaryotic translation initiation factor 4E (eIF4E) with potential antitumor activity. Antisense oligonucleotide ISIS EIF4ERx suppresses ...

nedaplatin

Pharmaceutical; Cancer drugs

A second-generation cisplatin analogue with antineoplastic activity. Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive ...