Cancer drugs

Cancer drugs

Drugs, agents used in the treatment of cancer or conditions related to cancer.

Industry: Pharmaceutical

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Cancer drugs

E2F1 pathway activator ARQ 171

Pharmaceutical; Cancer drugs

A second-generation E2F1 pathway activator with potential antineoplastic activity. ARQ 171 induces the expression of E2F transcription factor 1, thereby activating the E2F1-mediated checkpoint ...

epothilone KOS-1584

Pharmaceutical; Cancer drugs

A second-generation epothilone with potential antineoplastic activity. Epothilone KOS-1584 binds to tubulin and induces microtubule polymerization and stabilizes microtubules against ...

monoclonal antibody CC49

Pharmaceutical; Cancer drugs

A second-generation murine monoclonal antibody based on the antibody B72. 3 that is directed against tumor-associated glycoprotein 72 (TAG72). TAG72 is expressed by gastric, breast, pancreatic, ...

A second-generation, mixed-backbone, phosphorothioate antisense oligonucleotide (ODN) with potential antitumor activity. MG 98 is a highly specific inhibitor of translation of the mRNA for human DNA ...

EGFR/HER2 inhibitor AV-412

Pharmaceutical; Cancer drugs

A second-generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR/HER2 inhibitor AV-412 binds to and inhibits the epidermal growth factor receptor (EGFR) and ...

Aurora A kinase inhibitor MLN8237

Pharmaceutical; Cancer drugs

A second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase ...

gamma secretase inhibitor PF-03084014

Pharmaceutical; Cancer drugs

A selective gamma secretase (GS) inhibitor with potential antitumor activity. Gamma secretase inhibitor PF-03084014 binds to GS, blocking proteolytic activation of Notch receptors; Notch signaling ...