Cancer drugs

Cancer drugs

Drugs, agents used in the treatment of cancer or conditions related to cancer.

Industry: Pharmaceutical

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Cancer drugs

ingenol 3-angelate

Pharmaceutical; Cancer drugs

A selective small-molecule activator of protein kinase C (PKC) isolated from the plant Euphorbia peplus with potential antineoplastic activity. Ingenol 3-angelate (I3A) activates various protein ...

c-Met inhibitor AMG 208

Pharmaceutical; Cancer drugs

A selective small-molecule inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. C-Met inhibitor AMG 208 inhibits the ligand-dependent and ligand-independent activation of ...

tyrosine kinase inhibitor OSI-930

Pharmaceutical; Cancer drugs

A selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular ...

serine/threonine kinase inhibitor XL418

A selective, orally active small molecule, targeting protein kinase B (PKB or AKT) and ribosomal protein S6 Kinase (p70S6K), with potential antineoplastic activity. XL418 inhibits the activities of ...

Z-360

Pharmaceutical; Cancer drugs

A selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity. Z-360 binds to the gastrin/CCK-2 receptor, ...

peplomycin

Pharmaceutical; Cancer drugs

A semisynthetic analog of Bleomycin, a mixture of several basic glycopeptide antineoplastic antibiotics isolated from the fungus Streptomyces verticillus. Peplomycin forms complexes with iron that ...

lurtotecan

Pharmaceutical; Cancer drugs

A semisynthetic analogue of camptothecin with antineoplastic activity. Lurtotecan selectively stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. As a ...