Genetics

Genetics

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Genetics

Diploid

Biology; Genetics

Refers to the chromosome complement of normal body cells, which have two copies of each chromosome (one inherited from the mother and one from the father).

Dominant negative

Biology; Genetics

Alleles that cause an abnormal phenotype or disease by a mechanism that depends on the presence of an abnormal gene product interfering with the function of the products from a normal gene.

Double heterozygote

Biology; Genetics

An individual who is heterozygous for two mutations at two separate genetic loci that together are sufficient to manifest a phenotype. Differs from compound heterozygote.

Embryonic stem cell

Biology; Genetics

A pluripotential cell derived from the inner cell mass of an early-stage embryo that is capable of differentiating into cells derived from all three germ layers.

Epigenetic change

Biology; Genetics

A modification of a chromosome that does not alter the nucleotide base sequence, but alters the expression of a gene. Epigenetic changes may be stable in an individual, but may be reversed during ...

Epistasis

Biology; Genetics

The process by which variations at two or more genetic loci interact to produce phenotypes different from the individual effects of each variant. This process is often referred to as either a ...