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Genetics

Contributors in Genetics

Genetics

LOD score

Biology; Genetics

Logarithm of the odds” score. A quantitative measure of the statistical evidence of linkage between two genes. The LOD score depends on both the probability of cosegregation of the two genes during ...

Manhattan plot

Biology; Genetics

A type of plot used to display results of a GWAS study. Genomic coordinates are shown on the X-axis and the negative logarithm of the P-value for each SNP on the Y-axis. SNPs with the strongest ...

Marker

Biology; Genetics

A gene or other segment of DNA whose position on a chromosome is known and whose inheritance can be monitored.

Meiosis

Biology; Genetics

The specialised cell division that takes place when sex cells (sperm or egg cells) are produced. The members of each homologous pair of chromosomes separate from each other so that each sex cell ...

Mendelian inheritance

Biology; Genetics

A trait is said to have Mendelian inheritance if its genetic transmission can be explained by a Mendelian model of inheritance, such as autosomal dominant, autosomal recessive, or X-linked recessive ...

Methylation

Biology; Genetics

The addition of methyl groups to cytosine in DNA. Methylation, when followed by deamination, is a major pathway for mutation to thymine. Methylation also correlates with reduced gene transcription ...

Micro-RNA (miR)

Biology; Genetics

A small, non-coding RNA that regulates the stability or translation of a set of mRNAs.

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