9 Terms
Contributors in Genetics
Genetics
Mitochondrial genome
Biology; Genetics
The genetic material carried within mitochondria. At fertilization, all the mitochondria are derived from the egg, so mitochondrial genes display maternal inheritance.
Monogenic trait/monogenic disease
Biology; Genetics
Trait or disease with inheritance that can be explained by a single gene, in contrast to polygenic and complex diseases.
De novo mutation
Biology; Genetics
A novel genetic sequence variant introduced by a germline mutation. Often used to distinguish familial from sporadic cases of genetic disease.
Digenic inheritance
Biology; Genetics
Diseases caused by co-inheritance of mutations at two distinct genetic loci (ie, in two different genes).
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