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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

RAG-1 and RAG-2 (recombination activating genes)

Biology; Immunology

Genes and their products which are critically involved in V(D)J recombination in B and T cells.

rapamycin

Biology; Immunology

An immunosuppressive agent used to prevent transplantation rejection; blocks cytokine production.

receptor

Biology; Immunology

Generally a transmembrane molecule that binds to a ligand on the exterior surface of the cell, leading to biochemical changes inside the cell.

receptor editing

Biology; Immunology

Process by which the rearranged genes of a cell in the B-cell lineage may undergo a secondary rearrangement, generating a different antigenic specificity.

repertoire

Biology; Immunology

The complete library of antigenic specificities generated by either B or T lymphocytes to respond to foreign antigen.

reticuloendothelial system (RES)

Biology; Immunology

A general term for the network of phagocytic cells.

reverse transcriptase

Biology; Immunology

Enzyme which transcribes the RNA genome of a retrovirus into DNA; used in molecular biology to convert RNA into complementary DNA (cDNA).

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