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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

chimera

Biology; Immunology

Refers to an individual containing cellular components derived from another genetically distinct individual. In Greek mythology, an animal possessing the head of a lion, the body of a goat, and the ...

chronic granulomatous disease (CGD)

Biology; Immunology

A disorder that is inherited as an X-linked trait in two thirds of the cases and as an autosomal recessive trait in the remaining one third. The disease is characterized by an enzyme defect ...

chronic lymphocytic leukemia (CLL)

Biology; Immunology

A B cell leukemia in which long-lived small lymphocytes continually collect in the spleen, lymph nodes, bone marrow, and blood. CLL cells express a monoclonal immunoglobulin on their surface.

class II-associated invariant chain peptide (CLIP)

Biology; Immunology

A peptide of variable length cleaved from the invariant chain by proteases. CLIP remains associated with MHC class II molecules in an unstable form until it is removed by the HLA-DM protein.

classical complement pathway

Biology; Immunology

The mechanism of complement activation initiated by antigen-antibody aggregates and proceeding by way of C1 to C9.

clonal anergy

Biology; Immunology

The interaction of a B or T lymphocyte with an antigen leading to its functional inactivation. Anergy can result when the lymphocyte interacts with antigen in the absence of a second signal, usually ...

clonal deletion

Biology; Immunology

The loss of lymphocytes of a particular specificity due to contact with either self or foreign antigen.

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