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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

cross-reactivity

Biology; Immunology

The ability of an antibody, specific for one antigen, to react with a second antigen; a measure of relatedness between two different antigenic substances.

cytotoxic T lymphocyte-associated molecule-4 (CTLA-4)

Biology; Immunology

The high-affinity receptor for B7 molecules expressed on T cells.

cyclophosphamide

Biology; Immunology

An immunosuppressive drug that is more toxic for B than for T lymphocytes. Consequently, it is a more effective suppressor of humoral antibody synthesis than of cell-mediated immune reactions.

cyclosporin A

Biology; Immunology

An immunosuppresive drug that inhibits signaling from the T-cell receptor, preventing T-cell activation and effector function. It binds to cyclophilin, and this complex binds to an inactivates the ...

cytokine receptors

Biology; Immunology

Cellular receptors for cytokines. Binding of the cytokine to the cytokine receptor stimulates signal transduction resulting in new activities in the cell, such as growth, differentiation, or death.

cytokines

Biology; Immunology

Soluble substances secreted by cells, which have a variety of effects on other cells.

cytophilic antibody

Biology; Immunology

An antibody that attaches to a cell surface through its Fc region. It binds to Fc receptors on the cell surface. For example, IgE molecules bind to the surface of mast cells and basophils in this ...

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