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Immunology

Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.

Contributors in Immunology

Immunology

cytotoxic T cells

Biology; Immunology

T cells that can kill other cells. Most cytotoxic T cells are MHC class 1-restricted CD8 + T cells, but CD4 + T cells can also kill target cells in some cases.

cytotoxins

Biology; Immunology

are proteins made by cytotoxic T cells that participate in the destruction of target cells. Perforins and granzymes or fragmentins are the major defined cytotoxins.

D gene

Biology; Immunology

A small segment of immunoglobulin heavy-chain or T-cell receptor DNA, coding for the third hypervariable region of the receptors.

decay-accelerating factor (DAF)

Biology; Immunology

A membrane glycoprotein of normal human erythrocytes, leukocytes, and platelets, but absent from the red blood cells of paroxysmal nocturnal hemaglobulinuria patients. It facilitates dissociation of ...

degranulation

Biology; Immunology

A mechanism whereby cytoplasmic granules in cells fuse with the cell membrane to discharge the contents from the cell. A classic example is degranulation of the mast cell or basophil in immediate ...

delayed-type hypersensitivity (DTH)

Biology; Immunology

A form of cell-mediated immunity elicited by antigen present in the skin. The reaction is mediated by CD4 + T H 1 cells and involves release of cytokines and recruitment of monocytes and macrophages. ...

avidity

Biology; Immunology

The summation of multiple affinities, for example, when a polyvalent antibody binds to a polyvalent antigen.

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