14 Terms
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Immunology
Immunology is the study of the structuree and function of the immune system which is responsible for the protection from invading foreign macromolecules or organisms. It is a broad branch of biomedical science that covers the study of all aspects of the immune system in organisms. It deals with the physiological functioning of the immune system in both healthy states and immunological disorders (autoimmune diseases, hypersensitivities, immune deficiency, transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo.
Industry: Biology
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Immunology
C5 convertase
Biology; Immunology
A molecular complex that splits C5 into C5a and C5b in both the classical and the alternative pathway of complement activation.
C5 deficiency
Biology; Immunology
A very uncommon genetic disorder that has an autosomal recessive mode of inheritance. Individuals with this deficiency have a defective ability to form the membrance attack complex (MAC), which is ...
complement component 5b (C5b)
Biology; Immunology
The principal molecular product that remains after C5a has been split off by the action of C5 convertase on C5. It has a binding site for complement component C6 and complexes with it to begin ...
complement component 6 (C6)
Biology; Immunology
A complement component that participates in the membrane attack complex (MAC).
C6 deficiency
Biology; Immunology
A very uncommon genetic defect that has an autosomal recessive mode of inheritance in which affected individuals have only trace amounts of C6 in their plasma. They are defective in the ability to ...
complement component 7 (C7)
Biology; Immunology
A complement component that forms a complex with C5b67 is formed when C7 binds to C5b and C6. The complex has the appearance of a stalk with a leaf type of structure.
C7 deficiency
Biology; Immunology
A very uncommon genetic disorder with an autosomal recessive mode of inheritance in which the serum of affected persons contains only trace amounts of C7 in the plasma. They have a defective ability ...