Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

A method for reconstructing the order of random clones in a contig by identification of pairs with overlapping sequences. The DNA clones are deposited as parallel strips on a membrane, then strips of ...

affinity precipitation

Biology; Biochemistry

A technique for purification of proteins that depends upon reversible attachment to a ligand. A bis-ligand (or homofunctional ligand) is a double-headed molecule that can attach at each end to part ...

omic research

Biology; Biochemistry

Following the currency of 'genomics', additional words have been coined to denote the compilation of data bases as resources for future research and analysis; proteonomics for proteins, kinomics for ...

aromatic

Biology; Biochemistry

Descriptive of an organic compound that contains a planar cyclic structure of unusually stability due to the delocalization of electrons. The simplest aromatic compound is benzene, but the family of ...

randomization

Biology; Biochemistry

The migration of an isotope from one position in a labelled metabolite to another position due to the conversion of the metabolite into a symmetrical compound, in which labelled and non-labelled ...

unnatural amino acid mutagenesis

Biology; Biochemistry

A method for replacement of an amino acid residue of a protein with a non-naturally occurring amino acid. The mRNA that encodes the protein is modified to encode a nonsense suppressor codon. For ...

substrate phage

Biology; Biochemistry

A method for identification of the substrate specificity of a proteinase by its ability to select a phage that expresses a cleaveable polypeptide, which is one of a library of random amino acid ...