Molecular biology

Molecular biology

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Molecular biology

Walden inversion

Biology; Biochemistry

A change of the configuration at an asymmetrical carbon atom due to the entry from one side of the center of an attacking group, simultaneously with the departure from the other side of a leaving ...

concatenate

Biology; Biochemistry

A structure formed by two or more interlinked closed circular (cc)DNAs; formation occurs between the rapid replication of a ccDNA and the slow nicking of one of the ccDNAs to release it from the ...

catenane

Biology; Biochemistry

A structure formed by two or more interlinked closed circular (cc)DNAs; formation occurs between the rapid replication of a ccDNA and the slow nicking of one of the ccDNAs to release it from the ...

transgenic

Biology; Biochemistry

Descriptive of an animal that has developed in a surrogate mother from a fertilized ovum that had been injected with a recombinant DNA gene; contrasted with congenic, meaning of the same genetic ...

one-gene one-enzyme hypothesis

The proposal that arose from genetic studies on the effects on amino acid metabolism of mutations in Neurospora, that there is a one-to-one correspondence between enzymes and the genes that encode ...

exotoxin

Biology; Biochemistry

A disease-causing agent that is produced and secreted by a pathogen; contrasted with an endotoxin, which is an intrinsic component of the pathogen, e.g. the lipopolysaccharide of Gram-negative ...

quenching

Biology; Biochemistry

In fluorescence spectroscopy, a decrease in emission due to a variety of causes that dissipate energy of the excited state, e.g. transfer of energy to a non-fluorescent molecule such as molecular ...