Molecular biology

Molecular biology

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Molecular biology

Technical knock-out approach (TKO)

Biology; Biochemistry

Used for the construction of apoptosis-incapable mutations. Use of a cytokine to induce apoptosis in the vast majority of cultured cells allows the survival of only those that have deficient ...

A measure of the ability of a solution to maintain its pH in the face of the addition of acid or alkali; a capacity of 1 when 1 mol of acid (or alkali) is added to 1 litre causes a pH fall (or rise) ...

initiator tRNA

Biology; Biochemistry

The tRNA that recognizes the AUG start codon. In prokaryotes it can be charged to bear a formylmethionine residue (methionine in eukaryotes) which will become the N-terminus of the new protein.

green beard

Biology; Biochemistry

A conspicuous phenotype that allows behavioral differentiation among individuals of the species. When the consequent behavior is beneficial, the encoding gene can be considered a selfish gene.

orphon

Biology; Biochemistry

A displaced genetic element; a coding or non-coding sequence that usually occurs in a series of tandem repeats in a eukaryotic genome but appears in a location atypical of the species or strain.

toxin

Biology; Biochemistry

A natural poison, especially one of a class of proteins that act intracellularly to interrupt vital functions. see also endotoxin; see also exotoxin; see also ribosome-inactivating protein (RIP)

proteolipid

Biology; Biochemistry

A protein that is soluble in organic solvents, usually due to the presence of a significant number of fatty acids esterified to secondary hydroxy groups and/or fatty acylation of its N-terminus.