Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

An analysis based on Fourier's theorem that any periodic function may be reduced to a series of sine and cosine terms, each represented by an amplitude and a phase. The transformation is the casting ...

anisotropy

Biology; Biochemistry

A measure of the mobility of a fluorophore: A=(I

monoclonal antibody (mAb)

Biology; Biochemistry

An immunoglobulin preparation that is completely homogeneous, due to its formation by daughters of a single progenitor cell that has been programmed for the synthesis and secretion of one specific ...

ligase chain reaction (LCR)

Biology; Biochemistry

A technique for detection and amplification of target DNA sequences. Two oligodeoxynucleotides are synthesized which between them are complementary to the entire target sequence, one to the 5'-side ...

positional cloning (reverse genetics)

Biology; Biochemistry

The search for a gene (e.g. that for cystic fibrosis) with no knowledge of the gene product by locating it on the basis of linkage analysis with other genetic traits or individual polymorphisms in ...

initiation complex

Biology; Biochemistry

The ribosome charged with mRNA, initiation factors and methionyl-tRNA (in eukaryotes) or N-formylmethionyl-tRNA (in prokaryotes, mitochondria and chloroplasts) that is bound to the initiation codon.

spliceosome

Biology; Biochemistry

A complex of (small nuclear RNA)-protein complexes and other proteins that assemble on a pre-mRNA and catalyze the excision of an intron in a process mechanistically similar to group II ...