Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

An intermediate or transition state in phosphate reactions, in which an incoming oxygen atom displaces a leaving oxygen in a concerted reaction and forms a trigonal bipyramid in which the phosphorus ...

functional divergence ratio (FDR)

Biology; Biochemistry

A measure of the evolutionary selective pressure on a protein. In a family of homologous proteins, or the genes encoding them, the amino acid residues are categorized as functional (e.g. those at the ...

sandwich immunoassay

Biology; Biochemistry

A method for quantification of an antigen large enough to have two epitopes. The antigen serves as a bridge between an immobilized (captive) antibody attached to one epitope, and a radioisotope-, ...

exchange reaction

Biology; Biochemistry

A partial enzymic reaction, especially when only one of two substrates is present, in which chemical groups or single atoms of the substrate equilibrate with the medium, with a cofactor or with one ...

leucine scissors

Biology; Biochemistry

A supersecondary structure of some DNA-binding proteins; a coiled coil of two parallel -helices. Each is of about 30 residues in length and contains leucine residues at every seventh position, which ...

transmembrane domain

Biology; Biochemistry

A feature of most intrinsic proteins of plasma or vesicular membranes; a polypeptide sequence of about seven residues if β-sheet, up to 22 residues if α-helix, that connects extracellular to ...

cascade

Biology; Biochemistry

A series of enzymic reactions that at each step convert an inactive enzyme into an active enzyme, which in turn activates another inactive enzyme, and thus greatly amplifies the initial signal. In a ...