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Molecular biology
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Molecular biology
group transfer potential
Biology; Biochemistry
A quantitative measure of the strength of attachment of a moiety (the group) to the rest of the molecule; the difference in standard free energies between the group attached to the molecule and the ...
Ca2+-myristoyl switch
Biology; Biochemistry
The mechanism by which Ca 2+ signals a change in a myristoylated protein. In its non-liganded state, the acylated N-terminal amino group is buried in the protein's interior; upon binding to Ca 2+ , ...
adaptor hypothesis
Biology; Biochemistry
The proposal, made before the roles of mRNA and tRNA in protein synthesis were established, that a low-molecular-mass form of RNA provides the interface between each amino acid and the template. The ...
homomer
Biology; Biochemistry
A complex composed of only one kind of subunit; e.g. the neo-natal glycine-gated Cl - channel, which is composed of five α 2 subunits. This is contrasted with a heteromer, a complex composed of ...
hydrophobic bond
Biology; Biochemistry
The association of non-polar side chains of a protein that is driven by minimization of the relatively unfavorable interactions of water molecules with the non-polar groups, and maximization of the ...
isothermal titration calorimetry
Biology; Biochemistry
ITC; A technique for measuring binding affinities (free energy of binding) of molecules in the low millimolar to nanomolar range. The heat absorbed or released during binding under equilibrium ...
Michaelis-Menten kinetics
Biology; Biochemistry
The hyperbolic dependence of the rate of an enzymic reaction on substrate concentration that can be analyzed mathematically according to a model that requires the reaction to proceed through a ...
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