Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

The likelihood of finding an amino acid residue in a certain secondary structure, e.g. glycine in an α-helix. Data from statistical surveys, host-guest analysis, model peptides, directed mutagenesis ...

centimorgan (cM)

Biology; Biochemistry

A genetic measure of the distance that separates markers in the same chromosome, especially in describing a map of the chromosome; the distance that permits a 1% frequency of crossing over (1 morgan ...

transcription factor

Biology; Biochemistry

A protein that binds to a specific DNA sequence and enhances or suppresses transcription of the target gene. One class is the basic helix-loop-helix proteins; upon associating with another molecule ...

insulin

Biology; Biochemistry

A hormone secreted by the pancreas that binds to its specific cell surface receptor in tissues throughout the body. Insulin regulates multiple growth and metabolic actions of cells including glucose ...

gene conversion

Biology; Biochemistry

The replacement of an allele during crossing- over owing to mismatch repair of the heteroduplex intermediate; rather than being equally represented in daughter DNA strands, one allele is ...

Hill plot

Biology; Biochemistry

A graphical representation of binding data, especially for oxygen binding to haemoglobin; a plot of log(Y/(1-Y)) against logpO 2 , where Y is the fraction of binding sites occupied and pO 2 is the ...

multi-drug resistance (MDR)

Biology; Biochemistry

A phenomenon in which resistance that develops to one drug is manifested as resistance to many others, even those with very different structures; seen especially in chemotherapy. MDR is due to ...