Molecular biology

Molecular biology

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Molecular biology

carbohydrate

Biology; Biochemistry

One of a class of biological materials comprising sugars, polymers of sugars, and compounds related to them. The name derives from the basic sugar structure, (CH 2 O) n . The category includes ...

The variable domain of an immunoglobulin heavy (V H ) or light (V L ) chain, each of which can have considerable affinity for an antigen; produced in bacteria by biotechnological methods, whereby the ...

relaxation

Biology; Biochemistry

In kinetics and spectroscopy, the return to equilibrium of a macromolecule after a very brief perturbation of the environment, e.g. recovery of a protein from a sudden burst of energy that allows a ...

unfolded protein response (UPR)

Biology; Biochemistry

The cell's graded response to the presence of unfolded or misfolded proteins; initially, activation of the genes that support endoplasmic reticulum-associated protein degradation, then, if the system ...

Potter-Elvehjem homogenizer

Biology; Biochemistry

A device used to disrupt tissues. A cylindrical glass or hard polymer pestle rotates in a close-fitting tube and a suspension of the tissue particles is subjected to shearing forces as the pestle ...

genomic amplification with transcript sequencing (GAWTS)

Biology; Biochemistry

A DNA sequencing method that involves PCR amplification of the target and uses a primer with an attached phage promoter sequence, transcription to produce a single-stranded RNA and reverse ...

backbone cyclization

Biology; Biochemistry

An approach to design of polypeptide-like drugs, in which the C- or N-termini or side chains are linked to each other (end-to-end, side chain-to-side chain or end-to-side chain) in order to impose ...