Molecular biology

Molecular biology

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Molecular biology

zymogen

Biology; Biochemistry

A proenzyme; an inactive precursor of an enzyme, e.g. trypsiongen. Often, the zymogen is proteolytically activated by an endonuclease. In the case of some aspartate proteases, an acid-catalyzed ...

A variant of the usual fluorescence in situ hybridization technique in which non-mitosing cells are used to visualize a genetic marker on a (non-visible) chromosome by use of a fluorescence-labelled ...

primer

Biology; Biochemistry

An RNA sequence hybridized to a DNA template whose elongation by a DNA polymerase constitutes DNA synthesis. A random primer is a mixture of polynucleotides with all four bases at each sequence ...

anchored reference marker

Biology; Biochemistry

One of many genes that are used in mapping of chromosomes. Having a well defined locus within a chromosome, it is used to test for genetic linkage in order to localize new traits; also, in ...

mediator

Biology; Biochemistry

A complex of proteins that allows initiation of cell- and/or cell cycle-specific control of eukaryotic transcription. The complex bridges a (usually) upstream promoter DNA sequence bound to an ...

diauxie

Biology; Biochemistry

Bacterial growth in two stages which occurs when the bacteria are grown on two carbon sources, e.g. glucose and xylose. The first phase corresponds to consumption of one compound, followed by a lag ...

inhibitor

Biology; Biochemistry

In enzymology, a compound, or even a macromolecule, that blocks the action of an enzyme by reversible attachment in such a way as to prevent binding by the substrate (competitive inhibition), or by ...