Molecular biology

Molecular biology

Contributors in Molecular biology

Molecular biology

The minimal functional unit of skeletal muscle; roughly a cylinder bounded on its ends by Z-lines where the thin filaments are anchored; these extend towards the center. Thick filaments extend from ...

expressed sequence tag (EST)

Biology; Biochemistry

a partial coding sequence isolated at random from a cDNA library; like a sequence-tagged site for mapping genomic DNA, used as a landmark for identification and mapping of coding sequences, for ...

humanized antibody

Biology; Biochemistry

A chimaeric immunoglobulin of human and non-human origin. In order to minimize the possibility of the chimaera being antigenic in humans, only the hypervariable regions of a non-human monoclonal ...

mitochondrial permeability transition (MPT)

Biology; Biochemistry

The disruption of normal mitochondrial function by opening of non-specific MPT pores (MPTPs). This allows the free diffusion of small molecules and ions and if prolonged, can lead to necrosis. ...

differential centrifugation

Biology; Biochemistry

The fractionation of subcellular components according to their sedimentation behavior; separation into nuclei, mitochondria, lysosomes, microsomes (endoplasmic reticulum), ribosomes, cytosol, etc. by ...

Wood-Werkman reaction

Biology; Biochemistry

The proposed reaction, derived from the observed incorporation of isotopic CO 2 into succinate, by which CO 2 condenses with the 3-carbon compound pyruvate to form a 4-carbon compound, ...

secondary metabolism

Biology; Biochemistry

Those metabolic pathways, other than those for energy production and for biosynthesis of nucleic acids, proteins, structural components, etc., that are unique to an organism; especially those ...